I've been on many trips with my dragons and they've done very well. It provides a good opportunity for time outside to enjoy some natural surroundings and sunlight depending on where you go. My guys, especially Darwin, have really enjoyed roaming around new places (under supervision). If you can bring a large enclosure with you, go for it. Otherwise a pack n play style enclosure that you can fold out as needed should work. I typically bring an adjustable light stand with a fixture & basking light. A thermometer/temp gun to check your temps after you have everything set up for the day. Definitely bring a bag of cleaning supplies. I have a carrier that clips to a seatbelt which is a bit more secure for while driving. Enjoy the adventures. In my opinion, traveling with them in a reasonably safe and controlled manner provides them with valuable enrichment.